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Prof. Dr . John A. Jansen
Research interests include biomaterials and tissue regeneration, with a specific focus on the use of calcium phosphate ceramic as bone replacing materials. A major current project includes investigation of nanocomposites with bone inductive properties. Other research projects deal with the regeneration of dental tissues, like pulp, periodontal ligament and gingival mucosa. The knowledge obtained can be applied in dentistry as well as medicine. |
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Recent key publications J.S.Blum, M.A.Barry, A.G.Mikos, J.A.Jansen: In vivo evaluation of gene therapy vectors in ex vivo derived marrow stromal cells for bone regeneration in a rat critical size calavarial defect. Human Gene Therapy, 14; 1689-1701, 2003. P.Q.Ruhe, H.C.Kroese-Deutman, J.G.C.Wolke, P.H.M.Spauwen, J.A.Jansen: Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants in cranial defects in rabbits. Biomaterials, 25: 2123-2132, 2004 E.H.M.Hartman, J.A.Pikkemaat, J.J.Van Asten, J.W.M.Vehof, A.Heerschap, W.J.G.Oyen, P.H.M.Spauwen, J.A.Jansen: DBM induced ectopic bone formation in rats: in vivo study with follow-up by MRI, MRA and DEXA, Tissue Engineering, 10; 747-754, 2004. |
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