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Medical Microbiology
P.O. Box 9101
6500 HB NIJMEGEN
T: +31 24 3610577
F: +31 24 341666?

Robert Sauerwein, is head of Division of Medical Parasitology and Centre for Clinical Malaria Studies Nijmegen (CCMS Nijmegen) and is full professor of Tropical Parasitology.
Prof. R.W. Sauerwein

Interests are in the development and clinical testing of malaria vaccines and, in particular, Plasmodium falciparum transmission blocking vaccines. This involves antigen discovery and translational research where products enter the vaccine development pathway of product formulation, pre-clinical testing and clinical trials. Scientific interest is further focused on the analysis of both specific and non-specific immune correlates of protection and induction of protective immunity. Both experimental malaria infections and naturally acquired infections in malaria endemic areas are subjects of this analysis.

 
Recent key publications


Cornelis C. Hermsen, Sake J. de Vlas, G.J. van Gemert, Denise S.C. Telgt, Danielle F. Verhage en Robert W. Sauerwein. Testing vaccines in human experimental malaria: Statistical Analysis of parasitaemia measured by a quantitative real-time Polymerase Chain Reaction. American Journal Tropical Medicine and Hygiene 71 (2), 2004 - pp 196-201

Petra Schneider, Gerard Schoone, Henk Schallig, Danielle Verhage, Denise Telgt, Wijnand Eling, Robert Sauerwein (2004). Quantification of Plasmodium falciparum gametocytes in differential stages of development by quantitative nucleid acid seqence-based amplification. Molecular & Biochemical Parasitology. Molbio 9491 1-7.

J Teun Bousema, Louis C. Gouagna, Chris J. Drakeley, Annemiek M. Meutstege, Bernard A Okech, Ikupa NJ Akim, John C Beier, John I Githure and Robert W. Sauerwein. Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya. Malaria Journal 2004, 3:18 1-6.

M. van der Kolk, S.J. de Vlas, A. Saul, M. van de Vegte-Bolmer, W.M. Eling and W. Sauerwein. Evaluation of the standard membrane feeding assay (SMFA) for the determination of Malaria transmission-reducing activity using empirical data.Parasitology (2005), 130, 13-22