The main research interest is the development of bio-inspired materials and processes. By using a combination of synthetic techniques from organic chemistry, materials science and molecular biology, protein and peptide based materials are designed and constructed. Research lines include controlled drug delivery systems, artificial organelles, smart enzymes and hybrid materials comprising bioactive peptides and synthetic polymers.
Jan van Hest is professor of bio-organic chemistry at the Faculty of Science. He is the current Faculty's vice-dean of research. Since 2005 he is a member of the Young Academy of the Royal Netherlands Academy of Arts and Sciences.
van Dongen SF, Verdurmen WP, Peters RJ, Nolte RJ, Brock R, van Hest JC. Cellular Integration of an Enzyme-Loaded Polymersome Nanoreactor. Angew Chem Int Ed Engl. 49:7213-6, 2010.
Kim KT, Zhu J, Meeuwissen SA, Cornelissen JJ, Pochan DJ, Nolte RJ, van Hest JC. Polymersome Stomatocytes: Controlled Shape Transformation in Polymer Vesicles. J Am Chem Soc. 132:12522-4, 2010.
van den Heuvel M, Prenen AM, Gielen JC, Christianen PC, Broer DJ, Löwik DW, van Hest JC. Patterns of Diacetylene-Containing Peptide Amphiphiles Using Polarization Holography. J Am Chem Soc. 131:15014-7, 2009.
Carette N, Engelkamp H, Akpa E, Pierre SJ, Cameron NR, Christianen PC, Maan JC, Thies JC, Weberskirch R, Rowan AE, Nolte RJ, Michon T, Van Hest JC. A virus-based biocatalyst. Nat Nanotechnol. 2:226-9, 2007.
Keywords: Eye Disorders / Mitochondrial Disorders /
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