Huijnen, Martijn
Name:
Prof. Martijn Huynen


Function:
Full Professor


Theme:
Energy & Redox Metabolism



Profile

Research interests revolve around comparative genomics and molecular biology. He investigates how to exploit the wealth of genomic information that includes complete genome data, expression data, proteomics data and protein interaction data to obtain a better understanding of the working of the cell at a molecular level. Development of both concepts and protocols to turn noisy genomics data into reliable predictions of protein function and pathways, as well using these protocols to study specific biomolecular systems, such as the mitochondria, are among his main interests.

Martijn Huynen is a full professor and leader of the comparative genomics group within the NCMLS since 2001.


Recent key publications

  • van Noort V, Huynen MA. Combinatorial gene regulation in Plasmodium falciparum. Trends Genet. 22:73-8, 2006.

  • Gabaldón T, Rainey D, Huynen MA. Tracing the evolution of a large protein complex in the eukaryotes. J Mol Biol. 348:857-70, 2005.

  • Boxma B, de Graaf RM, van der Staay GW, van Alen TA, Ricard G, Gabaldón T, van Hoek AH, Moon-van der Staay SY, Koopman WJ, van Hellemond JJ, Tielens AG, Friedrich T, Veenhuis M, Huynen MA, Hackstein JH. An anaerobic mitochondrion that produces hydrogen. Nature. 434:74-9, 2005.

  • van Noort V, Snel B, Huynen MA. The yeast coexpression network has a small-world, scale-free architecture and can be explained by a simple model. EMBO Rep. 5:280-4, 2004. 

  • Snel B, Huynen MA. Quantifying modularity in the evolution of biomolecular systems. Genome Res. 14:391-7, 2004.


Keywords:  Malaria / Infectious diseases / Viral Infections / Energy Metabolism Disorders / Mitochondrial Disorders / Respiratory Tract Infections / Ataxia /


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